Witnessing systems at Newlife IVF

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What is IVF witnessing?

Witnessing in IVF refers to the process of confirming that the correct eggs, sperm and embryos are used for the correct patient at the correct time. It mitigates the risk of mismatched or misidentified samples.  At Newlife IVF, we take this responsibility extremely seriously, which is why we use both electronic and manual methods for accuracy and traceability.

RI Witness – electronic tracking for your peace of mind

Newlife IVF employs the RI Witness electronic witnessing system, which uses Radio Frequency Identification (RFID) technology to track and verify all eggs, sperm and embryos in the laboratory. Each patient is assigned an RFID card and every patient vessel (e.g. tubes, dishes and cryo-vessels) is labelled with a matching RFID tag, all of which are programmed with each patient’s unique IVF code and three points of identification.

How RI Witness works at Newlife IVF:

  • Patient RFID card: you are assigned an RFID card that is linked to your profile. This is used for identification during key procedures, such as egg retrieval and embryo transfer
  • RFID tags on all labware: all test tubes, dishes and cryo-vessels used to hold your biological material are labelled with RFID tags matched to your unique code and profile
  • Real-time monitoring: all lab workstations have RI Witness receivers that detect these tags automatically. The system logs and monitors every sample movement during the procedure in real-time
  • Mismatch protection: if a mismatch ever occurs – for example, if two different tags are brought into an area at the same time – RI Witness triggers an audible and visual alarm, and the procedure is stopped immediately to investigate and correct the issue. To further reduce the risk of mismatches, our embryologists strictly work with the biological materials of only one patient at a time at each workstation.

Cryostorage tracking

All biological material placed into cryostorage is barcoded and tagged using the RI Witness system.

Each cryo-vessel is labelled with:

  • Your full name
  • Date of birth
  • Unique IVF code
  • Date of freezing
  • Barcode is specific to the eggs, sperm or embryos stored inside.

These cold-resistant tags ensure identification is maintained even at ultra-low temperatures. When the material is removed from cryostorage, the barcode is scanned and cross-verified with RFID data and RI Witness, and double-witnessed by embryologists to confirm all points of identification.

Embryologist double-witnessing

In addition to RI Witness, every procedure is manually witnessed by two embryologists. This human double-checking system complements electronic witnessing and adds a layer of human judgement, visual verification and accountability.

Manual witnessing includes:

  • Verifying three patient identifiers (full name, DOB and patient unique IVF code)
  • Cross-referencing all vessel labels, barcodes and RI Witness tags
  • Confirming the procedure that is to take place
  • Checking the freeze dates and, for embryos, specific embryo numbers
  • Confirming the correct sample before and after thawing.

This step is essential when biological material is entering or exiting the laboratory, and before every procedure such as insemination, embryo transfer, embryo biopsy or cryopreservation.

Cryostorage safety – cryo-vessel monitoring and audits

Biological materials such as eggs, sperm and embryos are stored in specially designed devices (cryo-vessels) that are specific for very cold temperatures.  The cryo-vessel is tagged with a special tag that withstands very cold temperatures. The cyro-vessel includes the patient’s name, date of birth, unique IVF code and the date of the freezing, along with a unique barcode that is specific to that patient’s egg, sperm or embryo held within the individual device.

Every sample is:

  • Uniquely identified and traceable
  • Matched at any time using the RI Witness system and barcode
  • Manually verified when moved or thawed.

Regular audits are conducted, comparing all stored material against patient records, to ensure that what is in storage precisely matches what is documented in each individual file and the RI Witness log.

Thawing of stored biological material

When biological material is removed from cryostorage, the barcode is scanned and linked to the patient’s vessel via an RFID tag.  Removal of eggs, sperm or embryos from cryostorage is also witnessed manually by the embryologist performing the procedure and a second embryologist.  Before thawing the biological material, the embryologists will witness the three points of patient identification on the cryotag, the freeze date and, in the case of embryos, the specific embryo number on the cryotag. This is cross-referenced with the vessel the biological material will go into after thawing, and the RI witness system. A mismatch at any point will sound an alarm.

Only once all of these steps have been completed will the thawing of the eggs, sperm or embryos proceed.

Summary of witnessing measures at Newlife IVF:

  • Only one patient’s material is handled at each workstation at any time
  • All vessels and labware are RFID tagged and barcoded
  • The RI Witness system and the embryologist manual double-witnessing are used to confirm all details at every procedure
  • Cryostored material is linked to the patient via a barcode and the RI Witness system.
  • Regular audits verify that frozen material in storage matches patient records and the RI witness system.

Please ask us!

We understand IVF can be a time filled with both hope and uncertainty. Our systems are designed to mitigate risk and ensure your biological material is being managed with the highest levels of care, security and accountability. If you have any questions, please speak to a member of our team. We’re always happy to help you feel supported and informed.

The real cost of egg freezing – a candid conversation between Dr Nicole Hope and Victoria Devine

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Understanding egg freezing and the costs

Victoria Devine aims to make finance easier in every area of life, including fertility care. To do this, she strongly advocates that you take the time to do your research. Whether it be a new sweater, a first home or your future fertility – it pays to educate yourself first.

Victoria sat down with Dr Hope and asked her all about egg freezing. With a straightforward clarity that comes from her decades of fertility experience, Dr Hope outlined the egg freezing and IVF processes, and the differences between the two. She also explained how fertility care is timed to match the natural rhythms of your body. For this reason, a lot of fertility treatments are timed around your menstrual cycle.

‘The body has it all worked out and everything we do is actually trying to mimic or replicate what happens in the body,’ said Dr Hope.

Having covered the fundamentals, Victoria and Dr Hope then dived into the costs of egg freezing and IVF, as well as who is eligible for Medicare deductions to their fertility treatment. Dr Hope also discussed some of the patient financing options available to help people manage the costs of fertility care more comfortably.

Cutting out hidden fees at Newlife IVF

When it comes to any major expenses, Victoria recommends that it can be helpful to budget for both the known costs and any additional expenses that may come your way. In the case of egg freezing – depending on the healthcare provider you choose – you may have costs tacked on outside of the initial quote.

This is why at Newlife IVF, transparency with patients is a priority. It is rare for a patient to receive an unexpected or additional cost – and if there is a medical need for one, this will always be discussed beforehand.

‘People shouldn’t be getting too many extra costs outside what they are quoted,’ said Dr Hope.

Dr Hope also explained that all Newlife IVF patients receive an appointment with a member of the finance team before any treatment is started. This appointment helps people understand the costs of treatments and services, and the financing options available, which can help them make informed decisions about whether the treatment/service is right for them.

Infertility is more common than you may think

To complement Dr Hope’s fertility guidance, Victoria shared her own pregnancy experience, as well as the fertility journeys of some of her friends. It quickly became clear how varied fertility journeys can be and that there is no one-size-fits-all for family planning. This led Victoria to ask if there are any factors that can affect someone’s fertility.

Dr Hope explained that the quality of a woman’s eggs is one of the main contributors to their chances of having a baby. She added that although egg quality is affected by many factors, age is often the most crucial.

‘For women, the single biggest thing that predicts when we can get pregnant is our age,’ said Dr Hope.

Drawing on her proactive approach to fertility treatment, Dr Hope also talked through what people can do to improve their egg quality at any age.

A brief background about the webinar presenters

Victoria Devine is a multi-award-winning financial advisor, business owner, podcaster and author. She hosts the popular podcasts She’s on the Money and The Property Playbook, and is the CEO of Zella, a financial services company. Through all her ventures, Victoria aims to transform the way millennials think about money to make their financial dreams achievable.

Dr Nicole Hope is a highly experienced fertility specialist and the Medical Director of Newlife IVF. She also holds an advanced Certificate in Reproductive Endocrinology and Infertility (CREI). This is the highest level of qualification you can have in fertility care and less than 100 Australian fertility specialists have it! Above all, Dr Hope is passionate about helping her patients start or grow their families, and she prioritises the importance of providing the right information and support at each step of fertility care.

Learn more about the financial side of egg freezing

Watch the webinar for a full breakdown of egg freezing, the costs and the financing options available.

Sperm – the other half of the fertility equation

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Sperm contributes half of the genetic material needed for embryos to form. Issues related to sperm quality or function can lead to difficulties in embryo development, including issues with:

  • Genetic material quality: For successful fertilisation and healthy embryo development, ideally sperm DNA should remain intact. Damage to this genetic material – whether from oxidative stress, environmental factors or ageing – can lead to chromosomal abnormalities or improper DNA variations in the embryo, increasing the risk of developmental issues or miscarriage.
  • Sperm chromatin structure: Sperm chromatin, the DNA arranged within the sperm cell, must be tightly packed and properly organised to protect against DNA damage. Normal sperm chromatin structure is needed for successful fertilisation and embryo development. Abnormalities in chromatin structure can result in poor DNA repair, leading to embryo fragmentation (when tiny pieces of the cells that make up the embryo break away from the cells during division) or developmental arrest (when an embryo stops developing).
  • Sperm motility (movement): Sperm with low motility (asthenospermia) may struggle to reach and fertilise the egg through natural conception or IVF. Even if fertilisation occurs, impaired motility – depending on its cause – can impact early embryonic development, as the sperm may not deliver the essential signals and factors needed for optimal growth.
  • Sperm morphology: Sperm with abnormal morphology (size or shape) can affect fertilisation and embryo development. For instance, abnormal sperm may struggle to penetrate the egg, preventing fertilisation or causing abnormal embryo development. Structural defects, such as head or tail abnormalities, may prevent the sperm from properly interacting with the egg’s membrane, making fertilisation difficult in both natural conception and IVF.  Therefore, abnormal sperm morphology is indicative of low sperm quality.
  • Sperm epigenetics: Sperm carries epigenetic information – modifications that influence how genes function without changing the underlying DNA sequence. Disrupted sperm epigenetics can lead to improper gene expression in the embryo, increasing the risk of developmental issues, infertility or genetic disorders.
  • Oxidative stress: Sperm are vulnerable to oxidative stress – an imbalance between free radicals and antioxidants in the body – caused by factors such as smoking, alcohol consumption, environmental toxins or prolonged heat exposure. This oxidative damage can lead to DNA fragmentation, where sperm DNA strands break, potentially compromising embryo development after fertilisation.
  • Paternal age: As men age, their sperm quality may gradually decline, making conception more challenging. Although men do not experience a sudden decrease in fertility like women, ageing impacts sperm health, testicular function and pregnancy outcomes. For instance, older men may produce lower-quality sperm, reducing the chances of fertilisation. Sperm from older men are also more susceptible to DNA damage, which can increase the risk of miscarriage and DNA changes contributing to genetic conditions, including autism or schizophrenia in children.

Lifestyle changes to support sperm health

While some factors affecting sperm health are beyond control, lifestyle choices can play a significant role in improving sperm quality. Making positive changes may help enhance sperm function and increase the chances of successful conception. Suggestions that may assist with sperm quality include:

Keep the testicles cool

High temperatures can damage sperm. Avoid hot tubs, saunas, car seat warmers, placing your laptop on your lap for long periods, and carrying your mobile phone in your front pocket. Wear loose-fitting underwear to keep your testicles cool and prevent overheating.

Maintain a healthy diet

A balanced diet rich in vitamins, minerals and antioxidants from fruits, vegetables, nuts, seeds, whole grains and lean proteins can help protect sperm from damage.

Additionally, fertility-boosting nutrients such as vitamins C, E and folic acid, as well as zinc and selenium, have been linked to improved sperm quality. These are present in citrus fruits, leafy greens, eggs and nuts.

Consider fertility supplements

If you’re finding it difficult to obtain enough nutrients from your diet, you may wish to consider fertility supplements. Specifically, supplements such as zinc, folic acid, selenium and CoQ10 may support sperm health. However, please consult your fertility specialist before starting any new supplements.

Engage in regular exercise

Moderate physical activity can help maintain a healthy weight and improve overall health, which supports sperm production. However, excessive exercise or overtraining can have the opposite effect, leading to reduced testosterone levels and impaired sperm quality. Additionally, prolonged cycling (over 1.5 hours) should be avoided.

Avoid smoking and limit alcohol

Smoking and vaping are associated with poor sperm quality, including reduced count and motility and increased DNA damage. Quitting should be a priority for those looking to improve fertility.

Excessive alcohol consumption can also negatively affect sperm count and quality, so keep your intake to moderate levels for optimal reproductive health.

Maintain a healthy weight

Being overweight or obese can lead to hormonal imbalances, reduced sperm quality and lowered overall fertility. Achieving and maintaining a healthy weight through diet and exercise can help improve sperm health.

Avoid exposure to toxins

Minimise exposure to harmful chemicals such as pesticides, heavy metals and industrial toxins, as they can negatively affect sperm health. Avoid contact with pollutants in some cleaning products, plastics and air pollution – and skip drinking from plastic water bottles.

If chemical exposure is unavoidable (i.e. due to your work environment), always use appropriate protective equipment, such as gloves and masks, to reduce risk.

Attend regular medical assessments

Prioritising your overall health is essential, as conditions like diabetes, high blood pressure and infections can negatively affect sperm quality. Regular check-ups with your GP or healthcare professional can help detect and manage these issues early.

If you’re trying to conceive, inform your fertility specialist about any medications or supplements you’re taking, as some may impair sperm function.

Avoid drug use

Recreational drug use, such as marijuana or anabolic steroids, can significantly reduce sperm count and quality. If you’re using these substances, consider seeking help to quit.

Manage stress

Chronic stress can negatively impact hormone levels, affecting sperm production. Consider practising relaxation techniques like meditation, yoga, deep breathing, exercise or hobbies that help you relax.

Get enough sleep

Quality sleep is essential for overall health and plays a crucial role in hormone regulation. Poor sleep can disrupt hormone levels, including testosterone, which is vital for sperm production. To support reproductive health, prioritise restful sleep and aim for 7–9 hours of quality rest each night.

Limit caffeine intake

Excessive caffeine may negatively affect sperm quality. Limiting your intake to moderate levels (one or two cups per day) can be beneficial.

When to seek help

Making these lifestyle changes can help improve sperm quality over time. However, if you and your partner have been trying to conceive without success – 12 months if the female partner is under 35 years or six months if over 35 years – it may be time to seek specialist guidance. A fertility specialist can provide personalised advice and may recommend fertility testing to gain a clearer understanding of your reproductive health.

To book an appointment with one of our fertility specialists and explore your options, call Newlife IVF on (03) 8080 8933 or schedule a consultation online via our appointments page.

Single and ready to have a baby – what are my options?

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I’m a single woman – what are my options?

Donor sperm – clinic-recruited versus known donors

Essentially, there are two options for obtaining sperm: accessing donor sperm through a fertility clinic’s sperm bank, or using a sample provided by someone you know.

At Newlife IVF we have an on-site sperm bank containing samples recruited from local and international donors. The benefit of using sperm from our clinic-recruited donors is that it is thoroughly tested for infectious diseases and common genetic problems. After we freeze the sperm, it is then quarantined before donors are retested to make sure it is high quality and safe to use.

When you use a clinic-recruited donor, you also have the advantage of very clear legal boundaries. The donor has no legal connection to your child – they are not entitled to custody and do not have to pay child support. They also remain anonymous to a large extent; that is, you will not know the donor’s identity (but you will know their family medical history and some of their traits). However, your child can request that the donor’s identity be revealed to them when they turn 18.

If you choose not to go the clinic-recruited donor route, you may consider using a sperm sample from a friend or acquaintance. A benefit of using a known donor is you will likely have a good understanding of their appearance, background and traits. However, the social and legal boundaries are not as clear-cut as they are when using a clinic-recruited donor. Discussing expectations and creating firm boundaries with a known donor requires careful negotiation, and you may wish to seek legal advice on how best to proceed.

If you do decide to use a sample from someone you know, it’s best to involve a fertility clinic. That way, you can have the sample rigorously tested for safety and quality in the same way we test donor sperm.

In this video, Dr Chris Russell talks about donor sperm and its use in IVF and IUI procedures.

Insemination – how egg and sperm meet

The next consideration is how best to introduce the sperm sample to your egg. There are a few different options for insemination, and the most suitable will depend on your specific circumstances.

One possibility is home insemination. In this method, sperm is injected into the vagina using a syringe at home. As this mimics the natural fertilisation process, home insemination is effective when the donor has a normal sperm count. It is also one of the most cost-effective options. However, it does not afford the same degree of protection from infectious disease as undergoing a similar process via a fertility clinic.

The clinic-based alternative is intrauterine insemination (IUI). This is where a sperm sample is concentrated to contain a very high number of sperm. It is then injected directly into your uterus soon after your ovaries release an egg. Using a concentrated sperm sample increases the chances of a sperm fertilising your egg. Depending on your circumstances, your specialist may recommend combining IUI with a medication to stimulate the release of an egg from your ovaries, further increasing the chance of success.

The last option is in vitro fertilisation (IVF). In this process, several of your eggs will be introduced to sperm in laboratory dishes. When utilising clinic-recruited donor sperm, the best sperm may be selected and a single sperm injected directly into each egg, a process called intracytoplasmic sperm injection (ICSI). One of the best embryos resulting from IVF insemination will then be transferred back to your uterus. The rest can be frozen and stored for later use, if necessary.

Two embryologists performing the intracytoplasmic sperm injection procedure.In ICSI, a single sperm is injected into the centre of a mature egg.

There are a few reasons you may be advised to undergo IVF. If you have known infertility, you’re in your late 30s or early 40s (when female fertility naturally declines significantly), or you struggle to get pregnant through other forms of insemination, your specialist may recommend this procedure. Likewise, IVF may be advisable if you’re using a known sperm donor with low sperm quality or quantity for other methods of insemination. If you wish to do preimplantation genetic testing, which is the process of genetically testing your embryos before they are transferred to your uterus, IVF will be necessary. For more information about these procedures in relation to your particular circumstances, chat to your fertility specialist.

I’m a single man – what are my options?

To have a baby as a single man, you will need the help of an egg donor and a surrogate. According to Victorian law, these must be two different women.

You may choose to use a clinic-recruited egg donor, or a known donor, i.e. a friend, acquaintance, or a family member (note: the last is only okay if you are not using your own sperm). Egg donation must be altruistic in Australia, meaning no financial compensation is paid for providing eggs. Once the donor eggs are ready, your sperm will be introduced to them using IVF (discussed earlier in this article), and the best resulting embryo will be transferred to your surrogate’s uterus. If you are not using your own sperm, donor embryos may be an appropriate option for you.

It’s common to ask a friend, acquaintance or family member to be a surrogate. Surrogacy is also an altruistic process in Australia, however ‘reasonable’ medical costs can be paid by you. Keep in mind that in Victoria, multiple medical consultations, counselling sessions and legal advice are required for both you and the surrogate prior to proceeding. You will also need to seek permission from the Patient Review Panel (this is a legal requirement in Victoria), and the sperm or embryos must be quarantined. This process can take several months.

Seeking a surrogate overseas may also be an option. However, according to Australian law, this is only legal if it is altruistic. Be aware that this is a very expensive route and you will need to plan to potentially be overseas for a few months after your baby is born to organise their entry into Australia.

For advice related to your particular circumstances, you may wish to seek legal advice and talk to a fertility specialist. Unfortunately, Newlife IVF is not permitted to assist you in finding a surrogate (nor can any other IVF provider). However, our counsellors can certainly orientate you to the Victorian surrogacy community and provide support and information as you look for a potential surrogate.

Ready to have a baby on your own?

Make an appointment with one of our caring and experienced Newlife IVF fertility specialists to discuss the most appropriate way forward based on your medical history, circumstances and preferences. Call (03) 8080 8933 or book online and take the next step towards your dream.